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Treatments

Polynucleotides Regenerative Treatments

From £395

Polynucleotides
Polynucleotides skin regeneration
Stimulates collagen synthesis
Comprised of biopolymers DNA
Please call us or fill in the form below and we will be delighted to help with your enquiry.

 0207 386 0464


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Polynucleotides - Latest Regenerative Skin Treatments

Biostimulation Treatment to Kick-Start Skin Regeneration - Boost Collagen, Hydration & Skin Elasticity Naturally

Polynucleotides are sterilised DNA fragments used in injectable biostimulation treatments designed to regenerate skin from within. They work by boosting collagen and elastin production while reducing inflammation, improving skin elasticity, hydration, texture, and tone. Administered by experienced clinicians, polynucleotide treatments offer a non-surgical solution for rejuvenating the face, neck, and hands, promoting natural repair, a radiant complexion, and long-lasting, youthful-looking results.

Polynucleotides Reviews

Treatment Benefits

Time

15-30 minutes

Recovery

No downtime

Results

2-3 days

Results Duration

3-6 months

Polynucleotides Treatment Costs

Polynucleotides TreatmentCost per session
1x single PhilArt polynucleotides treatment session £395

Consultation

The cost of consultation with our doctors is £75. This is redeemable against the cost of treatment carried out on the same day.

Prices are a guide to the costs and the exact price can only be determined once the doctor has examined you in person.

Call 0207 386 0464 OR email  [email protected] for advice and help.

Polynucleotides Before & After Results and Videos

FAQ's

Polynucleotides Questions & Answers

Is polynucleotide a filler?

Polynucleotides don’t contain hyaluronic acid like fillers do. Instead, they are comprised of biopolymers DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) . In DNA there are two spiral chains of polynucleotide which are arranged in a helical fashion, while RNA is a single-stranded molecule.

What happens during a polynucleotides treatment?

Before the treatment a numbing cream can be applied to the patient, especially if there are multiple injections involved. Depending on the area of treatment, the polynucleotides can be injected via two methods. The first are very tiny needles, leaving tiny blebs on the surface which disappear usually after a few hours. Alternatively, a blunt-ended cannula may be used to spread the product evenly. The process usually takes about 20-30 minutes.

How long do polynucleotides treatment results last?

Results last around six to nine months on average, depending on the patient’s lifestyle and rate of ageing.

What are the potential complications, risks and side effects of polynucleotides?

The risks of polynucleotides are less than those of other injectable procedures, but this will depend on the practitioner’s experience and technique. However, unlike dermal filler, the treatment cannot be reversed as the product can’t be dissolved.

Side effects of polynucleotides are generally minimal, with the main potential side effects relating to the site of the injection, where patients may experience redness, swelling and bruising which should settle after one to two days. More serious side effects, such as allergic reactions, are extremely rare. As with all treatments, it’s important to carry out a thorough pre-treatment consultation to assess the patient’s suitability.

How quickly will I see results after polynucleotides treatment?

Unlike with dermal fillers, which have an instant effect, patients won’t notice the full benefits with polynucleotides immediatlely. This is because the action is at the cellular level and it takes time to become apparent, but patients may see some improvement after two to three weeks.

Who should not have polynucleotides?

Although polynucleotides are well tolerated by most patients and are suitable for all skin types, including sensitive skin, they are derived from fish, therefore are not appropriate for vegans. Allergic reactions are very unlikely as the particles of DNA are highly purified, so it can be safely injected into those who have allergies, including seafood allergies, with clinical trials reporting no allergic reactions to date. Polynucleotides are not suitable for patients who are pregnant or intending pregnancy, or who are breastfeeding.

How long does it take to recover from polynucleotides treatment?

Patients can generally return to normal activities straight after treatment.

In terms of aftercare, no makeup is advised for 12 hours and no laser treatments or excess heat for three weeks. SPF should be applied strictly for two to three weeks, and sunlight avoided.

References

  1. Bartoletti E, Cavallini M, Maioli L, Massirone A, Palmieri IP, Papagni M et al. Introduction to Polynucleotides Highly Purified Technology. Aesthetic Medicine. 2020 Oct-Dec; Vol.7 (1): 43-47.
  2. Collangelo MT. Govoni P, Beletti s, Squadrito F, Guizzardi S, Galli C. Polynucleotide biogel enchances tissue repair, matrix desposition and organization. J. of Biological Regulators & Homeostatic Agents. 2021; Vol.35 (1): 355-362.
  3. Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M et al. Consensus report on the use of PN-HPT (polynucleotides highly purified technology) in aesthetic medicine. J CosmetDermatol. 2021 Mar. 20 (3): 922-928. doi: 10.11.11/jocd.13679. Epub 2020 Sept. 21. PMID: 32799391; PMCID: PMC7984045.
  4. Cavallini M, Papagni M. Long Chain Polynucleotides Gel and Skin Biorevitalization. International Journal of Plastic Dermatology-ISPLAD. 2007; 3 (3): 27-32.
  5. Massirone A. Polynucleotides Highly Purified Technology and the face skin, a history of innovative skin priming. Aesthetic Medicine. 2021 Jan-Mar; Vol. 7 (1): 25-40.
  6. Araco A, Araco F. Preliminary Prospective and Randomized Study of Highly Purified Polynucleotide vs Placebo in Treatment of Moderate to Severe Acne Scars. Aesthet Surg J. 2021 Jun. 14; 41
  7. NP866-NP874. doi: 10.10.93/asj/sjab125. PMID: 33755110. PADB1222IMCAS | 38942 Product information for healthcare professionals   CE0373 PRKIT0123a
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